Description

3-Amino-2-Chloropyridine-4-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters as a critical intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific chloropyridine and carboxylic acid functionalities into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the pyridine core provides essential bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating complex chelating ligands used in catalysis and material science.
• Chemical Research & Development: Employed as a versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized colorants and functional dyes.
• Material Science Precursor: Acts as a monomer or functionalizing agent for advanced polymers and organic electronic materials.

Basic Information

Product Name	3-Amino-2-Chloropyridine-4-Carboxylic Acid
CAS No.	58483-94-6
Molecular Formula	C6H5ClN2O2
Molecular Weight	172.57 g/mol
Synonyms	2-Chloro-3-aminopyridine-4-carboxylic acid; 4-Pyridinecarboxylic acid, 3-amino-2-chloro-; 3-Amino-2-chloroisonicotinic acid; 2-Chloro-3-aminoisonicotinic acid; ACPCA; 3-Amino-2-chloro-4-pyridinecarboxylic acid; 2-Chloro-3-pyridinamine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Amino-2-Chloropyridine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for research and industrial use. Certificates of Analysis (COA) with full traceability are available upon request for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.