Description

2-Iodo-Isonicotinic Acid is a halogenated derivative of isonicotinic acid, serving as a versatile and valuable building block in advanced organic synthesis. Its core value proposition lies in its ability to introduce the iodine moiety and the isonicotinic acid scaffold into target molecules, enabling the development of novel compounds with specific functionalities. This intermediate is particularly needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as drug discovery, material science, and the synthesis of complex ligands.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting infectious diseases and central nervous system disorders.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging its halogenated pyridine structure.
• Ligand Synthesis: Serves as a starting material for creating complex chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and development of organic electronic materials and liquid crystals.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to construct biaryl systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme inhibition.

Basic Information

Product Name	2-Iodo-Isonicotinic Acid
CAS No.	58481-10-0
Molecular Formula	C6H4INO2
Molecular Weight	249.01 g/mol
Synonyms	2-Iodopyridine-4-carboxylic Acid; 4-Pyridinecarboxylic Acid, 2-Iodo-; Isonicotinic Acid, 2-Iodo-; 2-Iodoisonicotinic Acid; 2-Iodo-4-pyridinecarboxylic Acid
EINECS	Contact for details

Quality Control

Our 2-Iodo-Isonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.