Description

1,6-Methanonaphthalen-1(2H)-Amine, Octahydro-, Hydrochloride is a specialized bicyclic amine hydrochloride salt with a complex, rigid molecular architecture. This compound serves as a critical high-purity building block and key chiral intermediate in advanced synthetic chemistry, enabling the construction of sophisticated pharmacophores. It is primarily required by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly within neurological and complex organic synthesis programs.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders.
• Chiral Synthesis: Used in asymmetric synthesis to introduce stereochemical complexity, essential for creating enantiomerically pure therapeutic agents.
• Organic Chemistry Research: Acts as a valuable scaffold in methodological development and the exploration of new chemical spaces in academic and industrial R&D labs.
• Ligand and Catalyst Development: Employed in the design and synthesis of novel ligands or organocatalysts due to its unique bicyclic amine structure.
• Fine Chemical Production: Utilized in the manufacture of high-value, low-volume specialty chemicals for various advanced material applications.

Basic Information

Product Name	1,6-Methanonaphthalen-1(2H)-Amine, Octahydro-, Hydrochloride
CAS No.	58432-93-2
Molecular Formula	C₁₁H₁₈ClN
Molecular Weight	199.72 g/mol
Synonyms	Octahydro-1,6-methanonaphthalen-1-amine hydrochloride; 1-Aminooctahydro-1,6-methanonaphthalene hydrochloride; 1,6-Methano[10]annulene-1-amine, octahydro-, hydrochloride (8CI); 1-Aza-4-methyltricyclo[6.2.1.0²,⁷]undecane hydrochloride; Bicyclo[4.3.1]decan-10-amine, 1,2,3,4,5,6,7,8-octahydro-, hydrochloride; Endo-1-Aminooctahydro-1,6-methanonaphthalene hydrochloride
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and purified to meet exacting customer specifications, with purity typically exceeding 98.0% (HPLC). Comprehensive analytical control includes identity confirmation (IR, NMR), assay determination, and impurity profiling. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring full traceability and compliance with research and cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.