Description

Phenylphosphonous Acid Bis[(1R,2S,5R)-5β-Methyl-2α-(1-Methylethyl)Cyclohexyl] Ester is a high-purity, chiral organophosphorus compound that serves as a critical intermediate in advanced chemical synthesis. Its value lies in its role as a versatile ligand and building block for creating stereoselective catalysts and complex molecular architectures. This product is essential for research and development laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to develop novel active ingredients with high enantiomeric purity.

Application

• Asymmetric Catalysis: Employed as a chiral ligand or precursor for transition metal catalysts used in stereoselective hydrogenation, hydroformylation, and cross-coupling reactions.
• Pharmaceutical Intermediate: A key building block in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly for complex therapeutic agents.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides where specific stereochemistry is required for optimal biological activity and environmental profile.
• Material Science Research: Investigated for the development of chiral polymers, liquid crystals, and advanced functional materials with specific optical or electronic properties.
• Organic Synthesis Reagent: Functions as a phosphorus-based reagent in phosphorylation reactions and the construction of complex phosphonate and phosphinate esters.

Basic Information

Product Name	Phenylphosphonous Acid Bis[(1R,2S,5R)-5β-Methyl-2α-(1-Methylethyl)Cyclohexyl] Ester
CAS No.	58359-50-5
Molecular Formula	C32H55O2P
Molecular Weight	502.75 g/mol
Synonyms	(-)-Menthyl Phenylphosphonite; (1R,2S,5R)-(-)-Menthyl Phenylphosphonite; Phenylphosphonous Acid Bis(8-methyl-2-isopropyl-5-methylcyclohexyl) Ester; Phenylphosphonous Acid Di-[(1R,2S,5R)-(-)-Menthyl] Ester; (-)-Menthyl Phenylphosphinite; L-Menthyl Phenylphosphonite; Di-(-)-menthyl Phenylphosphonite
EINECS	Contact for details

Quality Control

Our production of Phenylphosphonous Acid Bis[(1R,2S,5R)-5β-Methyl-2α-(1-Methylethyl)Cyclohexyl] Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and chiral analysis to confirm identity, assay, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and moisture-sensitive; prolonged exposure to air should be avoided.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.