Description

1-Iodo-4-Nitronaphthalene is a halogenated nitronaphthalene derivative that serves as a versatile and valuable synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both an iodine substituent and a nitro group on the naphthalene ring system, makes it a critical precursor for constructing complex molecules through cross-coupling and functional group transformation reactions. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable building blocks for drug discovery and material science applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with naphthalene-based scaffolds.
• Agrochemical Research: Used in the development and production of novel herbicides, fungicides, and other crop protection agents.
• Material Science: Serves as a precursor for organic electronic materials, dyes, and pigments due to the naphthalene core's photophysical properties.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Negishi couplings to form new carbon-carbon bonds.
• Functional Group Transformation: The nitro group can be selectively reduced to an amine, providing a handle for further derivatization into amides, sulfonamides, or heterocycles.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis and coordination chemistry.

Basic Information

Product Name	1-Iodo-4-Nitronaphthalene
CAS No.	58258-66-5
Molecular Formula	C₁₀H₆INO₂
Molecular Weight	299.07 g/mol
Synonyms	4-Nitro-1-iodonaphthalene; 1-Iodo-4-nitro-naphthalene; Naphthalene, 1-iodo-4-nitro-; 4-Nitro-1-naphthyl iodide; 1-Iodo-4-nitronaphthalene; 1-(Iodo)-4-nitronaphthalene
EINECS	Contact for details

Quality Control

Our 1-Iodo-4-Nitronaphthalene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity determination, to meet exacting customer specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, ensuring full traceability and compliance with your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Solubility	Soluble in common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.