Description

2-Bromo-1-Ethoxy-4-Nitrobenzene is a versatile halogenated aromatic ether compound, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring bromine and nitro substituents on an ethoxybenzene core, makes it a valuable electrophile for constructing complex molecules. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where precise molecular architecture is paramount for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a halogenated aromatic scaffold.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides, where the nitro and bromo groups facilitate further functionalization.
• Material Science Research: Serves as a monomer or building block for creating specialized polymers and liquid crystals with tailored electronic properties.
• Dye and Pigment Manufacturing: Intermediate in the production of complex organic dyes and colorants, leveraging its nitro-aromatic structure.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig aminations to form biaryl and other advanced structures.
• Organic Synthesis & Process Development: A reliable starting material for medicinal chemistry and process R&D in fine chemical production.

Basic Information

Product Name	2-Bromo-1-Ethoxy-4-Nitrobenzene
CAS No.	58244-42-1
Molecular Formula	C8H8BrNO3
Molecular Weight	246.06 g/mol
Synonyms	1-Bromo-2-Ethoxy-4-Nitrobenzene; 2-Bromo-4-Nitrophenetole; 4-Nitro-2-Bromophenetole; 2-Ethoxy-4-Nitro-1-Bromobenzene; 4-Nitro-2-Bromo-1-Ethoxybenzene; 2-Bromo-4-Nitro-1-Ethoxybenzene; 1-Ethoxy-2-Bromo-4-Nitrobenzene; Phenetole, 2-bromo-4-nitro-
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-Ethoxy-4-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profile, and physical characteristics are provided with every shipment to guarantee consistency and traceability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.