Description

(S)-1,1,4A-Trimethyl-3,4,4A,5,6,7-Hexahydronaphthalen-2(1H)-One is a high-purity, chiral intermediate of significant importance in advanced organic synthesis. Its defined stereochemistry and complex decalin-like structure make it a valuable building block for creating optically active compounds. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel active ingredients with specific three-dimensional configurations.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in steroid-like or terpenoid-based therapeutic molecules.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where specific stereochemistry can influence biological activity and environmental profile.
• Fine Chemical Production: Serves as a sophisticated starting material or intermediate in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & Industrial Research: A valuable compound for methodological development in asymmetric synthesis, catalysis studies, and total synthesis of natural products.
• Material Science Precursor: Potential use in the synthesis of chiral ligands for catalysts or advanced organic materials with specific optical properties.

Basic Information

Product Name	(S)-1,1,4A-Trimethyl-3,4,4A,5,6,7-Hexahydronaphthalen-2(1H)-One
CAS No.	58193-60-5
Molecular Formula	C₁₃H₂₀O
Molecular Weight	192.30 g/mol
Synonyms	(S)-1,1,4a-Trimethyl-3,4,4a,5,6,7-hexahydro-2(1H)-naphthalenone; (4aS)-1,1,4a-Trimethyl-3,4,4a,5,6,7-hexahydro-2H-naphthalen-2-one; (S)-1,1,4a-Trimethyl-4,4a,5,6,7,8-hexahydro-3H-naphthalen-2-one; (S)-Decalone derivative; (S)-Octalone derivative; (S)-Perhydro-1,1,4a-trimethylnaphthalen-2-one; (S)-Tetrahydro-1,1,4a-trimethylnaphthalen-2-one isomer
EINECS	Contact for details

Quality Control

Our (S)-1,1,4A-Trimethyl-3,4,4A,5,6,7-Hexahydronaphthalen-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.