Description

1-o-Methyl-β-D-Glucuronic Acid, Sodium Salt is a high-purity, chemically defined derivative of glucuronic acid, serving as a critical building block and reference standard in advanced biochemical research and synthesis. Its primary value lies in its role as a key intermediate for the preparation of complex glycoconjugates and for studying enzymatic processes involving glucuronidation. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require precise and reliable substrates for glycosylation reactions, drug metabolism studies, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of glycosylated drugs, prodrugs, and targeted therapeutic agents.
• Biochemical Research: Used as a substrate or standard in enzymatic assays, particularly for glucuronosyltransferases (UGTs) involved in drug metabolism and detoxification pathways.
• Glycoconjugate Synthesis: Essential building block for the chemical and enzymatic synthesis of oligosaccharides, glycoproteins, and glycolipids.
• Analytical Reference Standard: High-purity grade for use in HPLC, LC-MS, and NMR as a calibration standard for quantitative and qualitative analysis.
• Cosmetic & Personal Care Actives: Potential ingredient in advanced skincare formulations targeting specific biological pathways.
• Academic & Industrial R&D: Fundamental reagent for investigating carbohydrate chemistry, metabolic engineering, and biosynthesis.

Basic Information

Product Name	1-o-Methyl-β-D-Glucuronic Acid, Sodium Salt
CAS No.	58189-74-5
Molecular Formula	C7H11NaO7
Molecular Weight	230.15 g/mol
Synonyms	Sodium 1-O-Methyl-β-D-glucopyranosiduronate; Methyl β-D-Glucopyranosiduronic Acid Sodium Salt; 1-O-Methyl-β-D-glucuronic acid sodium salt; β-D-Glucopyranosiduronic acid, methyl, sodium salt; Methyl β-D-glucuronate sodium salt; Sodium Methyl β-D-Glucuronate; 1-Methyl-β-D-glucuronic acid sodium salt
EINECS	Contact for details

Quality Control

Our 1-o-Methyl-β-D-Glucuronic Acid, Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed results from HPLC, NMR, and other relevant spectroscopic methods. Specifications are designed to meet the rigorous demands of research and cGMP-grade manufacturing for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. Handle under inert atmosphere if prolonged exposure is anticipated during use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.