Description

5-Amino-3,4-Dihydroquinolin-2(1H)-One is a high-purity, versatile heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its fused quinoline structure with an amino group, making it a critical intermediate for constructing complex molecules with potential biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Dye and Pigment Synthesis: Acts as a building block for creating specialized quinoline-based dyes and organic pigments.
• Material Science: Investigated as a monomer or precursor for advanced polymers and organic electronic materials.
• Academic & Contract Research: Essential for methodological studies in organic chemistry and for custom synthesis projects in CROs (Contract Research Organizations).
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in related chemical processes.

Basic Information

Product Name	5-Amino-3,4-Dihydroquinolin-2(1H)-One
CAS No.	58130-38-4
Molecular Formula	C9H10N2O
Molecular Weight	162.19 g/mol
Synonyms	5-Amino-1,2,3,4-tetrahydroquinolin-2-one; 5-Amino-3,4-dihydro-2(1H)-quinolinone; 5-Amino-1,2,3,4-tetrahydro-2-quinolone; 2-Quinolinone, 5-amino-1,2,3,4-tetrahydro-; 5-Aminotetrahydro-2-quinolone; 5-Amino-2-oxo-1,2,3,4-tetrahydroquinoline
EINECS	Contact for details

Quality Control

Our 5-Amino-3,4-Dihydroquinolin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.