Description

3-Hydroxy-4-Iodobenzoic Acid is a halogenated benzoic acid derivative that serves as a versatile building block in advanced organic synthesis. This compound is valued for its iodine substituent, which provides a reactive handle for further functionalization via cross-coupling reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for thyroid hormone analogs and other iodine-containing therapeutics.
• Agrochemical Research: Building block for developing novel herbicides, fungicides, and plant growth regulators that leverage the iodine moiety for bioactivity.
• Ligand Synthesis: Used to prepare specialized ligands for catalysis and metal-organic frameworks (MOFs) in material science.
• Diagnostic Agent Development: Intermediate in the production of contrast agents and radiolabeled compounds for medical imaging.
• Organic Electronic Materials: Monomer or dopant in the research and development of organic semiconductors and conductive polymers.
• Cross-Coupling Reactions: Essential substrate for Suzuki, Heck, and other palladium-catalyzed coupling reactions to construct biaryl systems.

Basic Information

Product Name	3-Hydroxy-4-Iodobenzoic Acid
CAS No.	58123-77-6
Molecular Formula	C7H5IO3
Molecular Weight	263.02 g/mol
Synonyms	4-Iodo-3-hydroxybenzoic acid; 3-Hydroxy-4-iodobenzoic acid; Benzoic acid, 3-hydroxy-4-iodo-; 4-Iodosalicylic acid; 3-Carboxy-4-hydroxyiodobenzene; 4-Iodo-3-carboxyphenol; 3-Hydroxy-4-iodo-benzoic acid; 58123-77-6
EINECS	Contact for details

Quality Control

Our production of 3-Hydroxy-4-Iodobenzoic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide full traceability and Certificates of Analysis (COA) are available for every shipment to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	215 - 220 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.