Description

4-Cyano-3-Iodobenzoic Acid is a versatile halogenated benzoic acid derivative that serves as a key synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a reactive cyano group and an iodine atom, makes it a valuable building block for constructing complex molecules through cross-coupling and functional group transformations. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzoic acid scaffold.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and polymers with specific optical or electronic properties.
• Cross-Coupling Reactions: The iodine atom is an excellent handle for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings to form biaryl and other conjugated systems.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological processes and target engagement.

Basic Information

Product Name	4-Cyano-3-Iodobenzoic Acid
CAS No.	58123-75-4
Molecular Formula	C8H4INO2
Molecular Weight	273.03 g/mol
Synonyms	3-Iodo-4-cyanobenzoic Acid; Benzoic acid, 4-cyano-3-iodo-; 4-Cyano-3-iodobenzoic acid; 3-Iodo-4-carboxybenzonitrile; 4-CN-3-I-C6H3-CO2H
EINECS	Contact for details

Quality Control

Our 4-Cyano-3-Iodobenzoic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Loss on Drying	< 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.