Description

10-(4'-Fluorobenzyl)-2,10-Dihydroimidazo[2,1-B]Quinazolin-5(3H)-One Hydrochloride is a high-purity, synthetically derived organic compound belonging to the fused quinazolinone class. This compound is a critical pharmaceutical intermediate valued for its role in the synthesis of complex bioactive molecules. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and oncology research.
• Chemical Reference Standard: Used for analytical method development, validation, and quality control in API manufacturing.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize pharmacological properties.
• Process Development: Employed in scaling up synthetic routes for preclinical and clinical trial material production.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and reaction mechanisms.

Basic Information

Product Name	10-(4'-Fluorobenzyl)-2,10-Dihydroimidazo[2,1-B]Quinazolin-5(3H)-One Hydrochloride
CAS No.	58059-17-9
Molecular Formula	C₁₈H₁₅FN₄O·HCl
Molecular Weight	362.80 g/mol
Synonyms	10-[(4-Fluorophenyl)methyl]-2,10-dihydroimidazo[2,1-b]quinazolin-5(3H)-one hydrochloride; 10-(4-Fluorobenzyl)-2,10-dihydro-3H-imidazo[2,1-b]quinazolin-5-one HCl; Imidazo[2,1-b]quinazolin-5(3H)-one, 10-[(4-fluorophenyl)methyl]-2,10-dihydro-, hydrochloride; 58059-17-9; UNII-9K7J3B8V3R
EINECS	Contact for details

Quality Control

Our production of 10-(4'-Fluorobenzyl)-2,10-Dihydroimidazo[2,1-B]Quinazolin-5(3H)-One Hydrochloride adheres to stringent quality protocols. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%; Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.