Description

7,8-Dichloro-1,2,3,4-Tetrahydroisoquinolinium Chloride is a high-purity, synthetically derived organic salt of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block (synthon) for the synthesis of complex molecules, particularly those targeting neurological and cardiovascular pathways. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of novel active pharmaceutical ingredients (APIs) and reference standards.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex isoquinoline-based drug candidates.
• Neurological Research: Used in the development of compounds for studying receptor binding and modulation within the central nervous system.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• API Synthesis: Employed in the controlled synthesis of Active Pharmaceutical Ingredients (APIs) requiring the specific 7,8-dichlorotetrahydroisoquinoline moiety.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, validation, and quality control in regulatory submissions.
• Academic & Institutional Research: Utilized in universities and research institutes for exploratory chemistry and pharmacological studies.

Basic Information

Product Name	7,8-Dichloro-1,2,3,4-Tetrahydroisoquinolinium Chloride
CAS No.	57987-77-6
Molecular Formula	C9H9Cl3N
Molecular Weight	245.53 g/mol
Synonyms	7,8-Dichloro-1,2,3,4-tetrahydroisoquinolin-2-ium chloride; 7,8-Dichloro-3,4-dihydroisoquinolin-2(1H)-ium chloride; 7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline hydrochloride; 7,8-Dichlorotetrahydroisoquinolinium chloride; 7,8-Dichloro-3,4-dihydroisoquinoline hydrochloride; 2H-Isoquinolinium, 7,8-dichloro-1,2,3,4-tetrahydro-, chloride (1:1)
EINECS	Contact for details

Quality Control

Our 7,8-Dichloro-1,2,3,4-Tetrahydroisoquinolinium Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D applications. A detailed Certificate of Analysis (COA) providing batch-specific results for purity, impurities, and other critical parameters is supplied with each order.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.