Description

3,5-Dichloro-4-(2,2,2-trifluoroethoxy)aniline is a high-purity, halogenated aniline derivative serving as a critical advanced intermediate in modern chemical synthesis. Its molecular structure, featuring both chloro and trifluoroethoxy substituents, makes it a valuable building block for creating complex molecules with specific electronic and steric properties. This compound is essential for research and development chemists and production specialists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Building block for developing next-generation herbicides, fungicides, and plant growth regulators with enhanced efficacy and environmental profiles.
• Liquid Crystal & OLED Materials: Used in the research and production of specialty electronic chemicals for displays and organic light-emitting diodes due to its halogenated aromatic core.
• Dye & Pigment Intermediate: Serves in the synthesis of specialized, high-performance dyes and pigments requiring halogenated aniline structures.
• Polymer Modifier: Acts as a functional monomer or cross-linking agent in the production of specialty polymers with tailored thermal and chemical resistance.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in medicinal chemistry, material science, and process development.

Basic Information

Product Name	3,5-Dichloro-4-(2,2,2-trifluoroethoxy)aniline
CAS No.	57946-62-0
Molecular Formula	C8H6Cl2F3NO
Molecular Weight	260.04 g/mol
Synonyms	4-Amino-2,6-dichloro-1-(2,2,2-trifluoroethoxy)benzene; 2,6-Dichloro-4-(2,2,2-trifluoroethoxy)aniline; 1-Amino-3,5-dichloro-4-(2,2,2-trifluoroethoxy)benzene; Benzenamine, 3,5-dichloro-4-(2,2,2-trifluoroethoxy)-; 3,5-Dichloro-4-(2,2,2-trifluoroethoxy)phenylamine; 4-(2,2,2-Trifluoroethoxy)-3,5-dichloroaniline
EINECS	Contact for details

Quality Control

Our 3,5-Dichloro-4-(2,2,2-trifluoroethoxy)aniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports applications requiring high standards, including cGMP intermediates for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.