Description

n-Acetyl-2-o-Benzyl-Neuraminic Acid Methyl Ester is a key protected derivative of sialic acid, a crucial carbohydrate moiety in glycobiology. This compound is essential for researchers and manufacturers requiring a stable, chemically modified intermediate for the synthesis of complex glycoconjugates and sialylated compounds. It is primarily utilized in the pharmaceutical and biotechnology sectors for the development of novel therapeutics, diagnostic tools, and for fundamental research in glycoscience and virology.

Application

• Glycoconjugate Synthesis: A critical building block for the chemical and enzymatic synthesis of sialylated oligosaccharides, glycoproteins, and glycolipids.
• Pharmaceutical Intermediates: Used in the research and development of sialidase inhibitors, antiviral agents, and anti-inflammatory drugs targeting sialic acid-mediated pathways.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies of sialyltransferases, neuraminidases, and other glycosyltransferases.
• Diagnostic Development: Employed in the creation of probes and assays for detecting pathogens, such as influenza viruses, that interact with sialic acid receptors.
• Glycoengineering: A valuable tool for modifying cell surface glycans to study cell-cell interactions, signaling, and immune responses.
• Standards and References: Used as a high-purity analytical standard in HPLC, MS, and NMR for quality control and method validation in related research.

Basic Information

Product Name	n-Acetyl-2-o-Benzyl-Neuraminic Acid Methyl Ester
CAS No.	57777-97-6
Molecular Formula	C₂₁H₂₉NO₉
Molecular Weight	439.46 g/mol
Synonyms	5-Acetamido-2,6-anhydro-3,5-dideoxy-D-glycero-D-galacto-non-2-enonic Acid Methyl Ester 9-Benzyl Ester; Methyl 5-acetamido-9-O-benzyl-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranosidonate; 9-O-Benzyl-N-acetylneuraminic Acid Methyl Ester; Benzyl-Protected Sialic Acid Methyl Ester; N-Acetyl-9-O-benzylneuraminic Acid Methyl Ester; Sialic Acid Benzyl Ester Methyl Ester Derivative
EINECS	Contact for details

Quality Control

Our n-Acetyl-2-o-Benzyl-Neuraminic Acid Methyl Ester is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and moisture. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our quality commitment supports applications requiring high-purity biochemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.