Description

2''-Cyano-1,1''-Biphenyl-2-Carboxylic Acid is a high-purity biphenyl derivative featuring both cyano and carboxylic acid functional groups, making it a versatile and valuable synthetic intermediate. Its primary value lies in its role as a key building block for the synthesis of complex organic molecules, particularly in advanced pharmaceutical research and development. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for constructing active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, particularly those with biphenyl or aryl-aryl coupled structures.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the biphenyl scaffold imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Advanced Material Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers where its molecular structure contributes to desired electronic or physical properties.
• Chemical Research & Development: A versatile building block for academic and industrial research into new chemical entities and reaction methodologies.
• Custom Synthesis: The foundation for contract manufacturing organizations (CMOs) producing bespoke fine chemicals for client-specific projects.

Basic Information

Product Name	2''-Cyano-1,1''-Biphenyl-2-Carboxylic Acid
CAS No.	57743-13-2
Molecular Formula	C₁₄H₉NO₂
Molecular Weight	223.23 g/mol
Synonyms	[2,2'-Biphenyl]-dicarboxylic acid, 2'-cyano-; 2'-Cyano[1,1'-biphenyl]-2-carboxylic acid; 2-Cyano-2'-biphenylcarboxylic acid; 2'-Cyano-biphenyl-2-carboxylic acid; o-Cyano-o'-biphenylcarboxylic acid; 2-Carboxy-2'-cyanobiphenyl; Biphenyl-2-carboxylic acid, 2'-cyano-
EINECS	Contact for details

Quality Control

Our 2''-Cyano-1,1''-Biphenyl-2-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis applications. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality parameters. Our commitment to consistent quality and traceability supports your regulatory and process development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.