Description

2-Keto-3-Deoxyoctonate-5-Phosphate is a key phosphorylated intermediate in the biosynthesis of bacterial lipopolysaccharides (LPS) and sialic acids. This compound matters significantly for researchers and manufacturers focused on carbohydrate chemistry, glycobiology, and the development of novel therapeutics or diagnostic tools. It is primarily needed by biochemical research institutions, pharmaceutical R&D departments, and companies specializing in the synthesis of complex carbohydrates, bacterial antigens, or metabolic pathway inhibitors.

Application

• Biochemical Research: Critical substrate for studying the CMP-KDO synthetase enzyme and the KDO biosynthesis pathway in Gram-negative bacteria.
• Glycobiology Studies: Used in the enzymatic or chemical synthesis of complex oligosaccharides and glycoconjugates for structural and functional analysis.
• Pharmaceutical Development: Serves as a precursor or intermediate in the research of novel antibiotics, vaccines, and anti-inflammatory agents targeting bacterial endotoxins.
• Enzyme Assay Substrate: Employed as a specific substrate in high-throughput screening assays to identify potential inhibitors of bacterial LPS biosynthesis.
• Metabolic Pathway Analysis: Utilized in metabolic labeling and tracer studies to elucidate pathways in bacterial systems and host-pathogen interactions.
• Reference Standard: Acts as a high-purity analytical standard for quality control in related biopharmaceutical manufacturing and research.

Basic Information

Product Name	2-Keto-3-Deoxyoctonate-5-Phosphate
CAS No.	57717-01-8
Molecular Formula	C8H13O11P
Molecular Weight	316.15 g/mol
Synonyms	KDO-5-P; 3-Deoxy-D-manno-oct-2-ulosonic acid 5-phosphate; 5-O-Phosphono-3-deoxy-D-manno-oct-2-ulosonic acid; 2-Keto-3-deoxyoctulosonate-5-phosphate; KDO5P; 3-Deoxy-D-manno-octulosonate 5-phosphate; 5-Phospho-3-deoxy-D-manno-oct-2-ulosonate
EINECS	Contact for details

Quality Control

Our 2-Keto-3-Deoxyoctonate-5-Phosphate is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for advanced biochemical research. Certificates of Analysis (COA) with detailed chromatographic data and spectral information are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This hygroscopic and potentially light-sensitive material should be handled under inert atmosphere when appropriate and allowed to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.