Description

Pyrazolidine, N1-Boc Protected is a high-purity, protected heterocyclic amine building block essential for advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise molecular architecture, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized in pharmaceutical R&D, agrochemical synthesis, and advanced material science where the introduction of a protected pyrazolidine moiety is required.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the pyrazolidine core for biological activity.
• Peptide Mimetics & Conjugation: Serves as a versatile scaffold for creating peptide analogs and for bioconjugation strategies in medicinal chemistry.
• Ligand Synthesis for Catalysis: Employed in the preparation of specialized ligands for asymmetric catalysis and transition metal complexes.
• Academic & Contract Research: A valuable reagent for methodological development and exploration of new heterocyclic chemistry in academic and CRO settings.
• Material Science Precursor: Potential use as a monomer or functionalizing agent in the synthesis of specialized polymers and smart materials.

Basic Information

Product Name	Pyrazolidine, N1-Boc Protected
CAS No.	57699-91-9
Molecular Formula	C8H16N2O2
Molecular Weight	172.23 g/mol
Synonyms	1-Boc-pyrazolidine; tert-Butyl 1-pyrazolidinecarboxylate; N-(tert-Butoxycarbonyl)pyrazolidine; 1-(tert-Butoxycarbonyl)pyrazolidine; Pyrazolidine-1-carboxylic acid tert-butyl ester; Boc-pyrazolidine; N-Boc-pyrazolidine; 1-N-Boc-pyrazolidine
EINECS	Contact for details

Quality Control

Our Pyrazolidine, N1-Boc Protected is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, supporting compliance with cGMP and ICH Q7 guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.