Description

1-(2-Chlorobenzyl)Piperidin-4-Amine Dihydrochloride is a high-purity, synthetically derived organic salt of significant interest in advanced pharmaceutical research and development. This compound serves as a critical pharmacological intermediate and building block for the synthesis of more complex active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical manufacturers and contract research organizations (CROs) engaged in the discovery and development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates targeting central nervous system (CNS) disorders.
• Chemical Reference Standard: Used for analytical method development, validation, and quality control in API manufacturing.
• Medicinal Chemistry Research: Employed as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity and selectivity.
• Process Chemistry Development: Serves as a starting material for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) conditions.
• Biochemical Research: Used in vitro studies to investigate interactions with specific biological targets, such as receptors or enzymes.

Basic Information

Product Name	1-(2-Chlorobenzyl)Piperidin-4-Amine Dihydrochloride
CAS No.	57645-60-0
Molecular Formula	C12H18Cl2N2
Molecular Weight	261.19 g/mol
Synonyms	4-Amino-1-(2-chlorobenzyl)piperidine dihydrochloride; 1-[(2-Chlorophenyl)methyl]-4-piperidinamine dihydrochloride; 1-(2-Chlorobenzyl)-4-aminopiperidine dihydrochloride; 4-Piperidinamine, 1-[(2-chlorophenyl)methyl]-, dihydrochloride; 1-(2-Chlorobenzyl)piperidin-4-ylamine dihydrochloride; 2-Chlorobenzyl-4-aminopiperidine dihydrochloride; 1-(o-Chlorobenzyl)-4-aminopiperidine dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(2-Chlorobenzyl)Piperidin-4-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.