Description

2-Amino-3-Hydroxy-n-Methylpropanamide is a versatile amino alcohol derivative with significant utility in advanced organic synthesis. Its bifunctional structure, featuring both amino and hydroxyl groups, makes it a valuable chiral building block and intermediate for creating complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly for neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis and metal complex formation.
• Peptide Mimetics & Modifications: Incorporated into peptide chains to alter physicochemical properties and biological activity.
• Polymer & Resin Modifier: Imparts hydrophilicity and reactivity into polymer backbones for specialty coatings and adhesives.
• Bioconjugation & Linker Chemistry: Utilized in the development of cleavable linkers for antibody-drug conjugates (ADCs) and diagnostic probes.

Basic Information

Product Name	2-Amino-3-Hydroxy-n-Methylpropanamide
CAS No.	57645-10-0
Molecular Formula	C₄H₁₀N₂O₂
Molecular Weight	118.13 g/mol
Synonyms	N-Methylserinamide; 2-Amino-3-hydroxy-N-methylpropanamide; 3-Hydroxy-2-(methylamino)propanamide; L-Serinamide, N-methyl-; (2S)-2-Amino-3-hydroxy-N-methylpropanamide; H-Ser-NHMe; Serinamide, N-methyl-
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Hydroxy-n-Methylpropanamide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) and spectroscopic results (NMR, IR) are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect purity and stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.