Description

1,3-Dioxolane-4-Methanol, 2,2,5-Trimethyl-, cis- is a specialized heterocyclic compound featuring a dioxolane ring fused with a methanol group, offering unique reactivity and solvating properties. This chemical is valued as a versatile chiral building block and solvent intermediate in advanced organic synthesis. It is primarily needed by research and development laboratories, fine chemical manufacturers, and pharmaceutical companies for applications requiring high-purity, structurally complex intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Utilized as a building block in stereoselective reactions to construct molecules with defined three-dimensional configurations.
• Ligand and Catalyst Preparation: Acts as a precursor for the development of novel ligands and organocatalysts used in catalytic processes.
• Specialty Solvent & Additive: Functions as a high-boiling, polar aprotic solvent or an additive in formulations requiring specific solvation power.
• Polymer Chemistry: Employed as a monomer or cross-linking agent in the production of specialty polymers and resins.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides.
• Flavor & Fragrance Industry: Potential intermediate for the synthesis of complex aroma chemicals.
• Academic & Industrial Research: A valuable reagent for methodological development and exploration of new chemical spaces in organic chemistry.

Basic Information

Product Name	1,3-Dioxolane-4-Methanol, 2,2,5-Trimethyl-, cis-
CAS No.	57626-73-0
Molecular Formula	C7H14O3
Molecular Weight	146.18 g/mol
Synonyms	cis-2,2,5-Trimethyl-1,3-dioxolane-4-methanol; (4R,5S)-2,2,5-Trimethyl-1,3-dioxolane-4-methanol; (cis)-2,2,5-Trimethyl-4-hydroxymethyl-1,3-dioxolane; 4-Hydroxymethyl-2,2,5-trimethyl-1,3-dioxolane (cis); D-Glyceraldehyde Acetonide; (R)-Glyceraldehyde Acetonide (common name for specific enantiomer); A chiral dioxolane derivative; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolane-4-Methanol, 2,2,5-Trimethyl-, cis- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials. Due to its organic solvent nature and potential sensitivity, it is recommended to store under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (cis-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.