Description

5-Chloromethyl-3-(4-Nitro-Phenyl)-[1,2,4]Oxadiazole is a specialized heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both a reactive chloromethyl handle and a nitro-substituted aromatic ring, makes it a versatile precursor for constructing complex pharmacophores and functional materials. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science Research: Serves as a building block for creating advanced polymers, liquid crystals, or organic electronic materials due to its rigid, conjugated structure.
• Chemical Biology Probe Development: Utilized to create tagged or functionalized molecules for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke intermediates for client projects.

Basic Information

Product Name	5-Chloromethyl-3-(4-Nitro-Phenyl)-[1,2,4]Oxadiazole
CAS No.	57611-19-5
Molecular Formula	C9H6ClN3O3
Molecular Weight	239.62 g/mol
Synonyms	5-(Chloromethyl)-3-(4-nitrophenyl)-1,2,4-oxadiazole; 3-(4-Nitrophenyl)-5-(chloromethyl)-1,2,4-oxadiazole; 4-Nitro-α-(5-chloromethyl-1,2,4-oxadiazol-3-yl)benzene; 1,2,4-Oxadiazole, 5-(chloromethyl)-3-(4-nitrophenyl)-; 57611-19-5; p-Nitro-α-(5-chloromethyl-1,2,4-oxadiazol-3-yl)benzene
EINECS	Contact for details

Quality Control

Our 5-Chloromethyl-3-(4-Nitro-Phenyl)-[1,2,4]Oxadiazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.