Description

(4R)-8β-[2-(3-Furyl)Ethyl]-4Aα,5,6,7,8,8A-Hexahydro-4-Methyl-7-Methylene-3H-4α,8Aα-Propano-1H-2-Benzopyran-1-One is a complex, high-purity organic compound featuring a unique fused ring system with a furan moiety, making it a valuable advanced pharmaceutical intermediate and a versatile building block for synthetic chemistry. Its intricate molecular architecture is critical for research and development in creating novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily sought by pharmaceutical R&D laboratories and specialty chemical manufacturers engaged in process development and the synthesis of complex target molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block in the multi-step synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and anti-inflammatory drug research.
• Organic Synthesis Research: Serves as a sophisticated precursor for exploring new chemical reactions and constructing complex polycyclic frameworks in academic and industrial R&D settings.
• Asymmetric Catalysis Studies: Used as a substrate or ligand precursor in the development and testing of new chiral catalysts due to its defined stereochemistry.
• Reference Standard: Employed as a high-purity analytical standard in method development and quality control for related pharmaceutical processes.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals requiring a specific, complex molecular scaffold for advanced material or agrochemical applications.

Basic Information

Product Name	(4R)-8β-[2-(3-Furyl)Ethyl]-4Aα,5,6,7,8,8A-Hexahydro-4-Methyl-7-Methylene-3H-4α,8Aα-Propano-1H-2-Benzopyran-1-One
CAS No.	57459-42-4
Molecular Formula	C20H24O3
Molecular Weight	312.41 g/mol
Synonyms	8β-[2-(3-Furyl)ethyl]-4aα,5,6,7,8,8a-hexahydro-4-methyl-7-methylene-3H-4α,8aα-propano-1H-2-benzopyran-1-one; (4R)-8β-(2-Furan-3-ylethyl)-4aα,5,6,7,8,8a-hexahydro-4-methyl-7-methylene-3H-4α,8aα-propano-1H-isochromen-1-one; 4α,8aα-Propano-1H-2-benzopyran-1-one, 8β-[2-(3-furanyl)ethyl]-4aα,5,6,7,8,8a-hexahydro-4-methyl-7-methylene-, (4R)-; Furan-based propano-benzopyranone derivative.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support development and commercial projects requiring compliance with cGMP and ICH Q7 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be sensitive to prolonged exposure to heat and moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.