Description

trans-7,8-Dihydroxy-7,8-Dihydrobenzo[A]Pyrene Dibenzoate is a high-purity, synthetic derivative of benzo[a]pyrene, a polycyclic aromatic hydrocarbon (PAH). This compound is of significant value as a critical reference standard and metabolite in toxicological and environmental research. It is primarily required by analytical laboratories, research institutions, and pharmaceutical companies engaged in studying PAH metabolism, DNA adduct formation, and carcinogenesis.

Application

• Analytical Reference Standard: For the qualitative and quantitative analysis (e.g., via HPLC, GC-MS) of benzo[a]pyrene metabolites in complex matrices.
• Toxicology Research: As a key metabolite in studies investigating the metabolic activation pathways and carcinogenic mechanisms of benzo[a]pyrene.
• Biomarker Development: Used in the development and validation of assays to detect and quantify specific DNA adducts for exposure assessment.
• Environmental Monitoring: Serves as a standard for monitoring PAH pollution and assessing human exposure risks from environmental sources.
• Pharmaceutical Research: Employed in studies focused on chemoprevention and the development of agents that inhibit PAH-induced carcinogenesis.
• Quality Control: For calibrating equipment and validating methods in laboratories that test for PAH content in products like fuels, oils, and food.

Basic Information

Item	Details
Product Name	trans-7,8-Dihydroxy-7,8-Dihydrobenzo[A]Pyrene Dibenzoate
CAS No.	57405-08-0
Molecular Formula	C34H22O4
Molecular Weight	494.54 g/mol
Synonyms	trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene dibenzoate; 7,8-Dihydro-7,8-dihydroxybenzo[a]pyrene dibenzoate; Benzo[rst]pentaphene-7,8-diol, 7,8-dihydro-, 7,8-dibenzoate, (7R,8R)-rel-; BPDE Dibenzoate (derivative); Benzo[a]pyrene-7,8-dihydrodiol-7,8-dibenzoate; trans-BP-7,8-diol-7,8-dibenzoate; (±)-trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene 7,8-dibenzoate
EINECS	Contact for details

Quality Control

Our trans-7,8-Dihydroxy-7,8-Dihydrobenzo[A]Pyrene Dibenzoate is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC purity analysis and structural confirmation (IR, NMR), to ensure identity, potency, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.