Description

4-Chloro-8-Hydroxyquinoline is a versatile halogenated quinoline derivative that serves as a critical synthetic intermediate and functional building block. This compound matters for its role in constructing complex molecules, particularly in the development of pharmaceuticals and advanced materials. It is needed by research institutions, pharmaceutical manufacturers, and fine chemical producers engaged in synthesis, medicinal chemistry, and material science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antimicrobial and anti-parasitic agents.
• Medicinal Chemistry Research: Used as a core scaffold or building block for developing novel drug candidates and conducting structure-activity relationship (SAR) studies.
• Coordination Chemistry: Acts as a chelating ligand for metal ions, useful in catalysis and the preparation of metal-organic frameworks (MOFs).
• Agrochemical Synthesis: Intermediate in the production of certain fungicides and plant protection agents.
• Material Science: Building block for organic electronic materials, dyes, and pigments due to its conjugated quinoline structure.
• Analytical Chemistry: Can be employed as a reagent or standard in chromatographic analysis and method development.

Basic Information

Product Name	4-Chloro-8-Hydroxyquinoline
CAS No.	57334-36-8
Molecular Formula	C9H6ClNO
Molecular Weight	179.60 g/mol
Synonyms	8-Hydroxy-4-chloroquinoline; 4-Chloro-8-quinolinol; 4-Chloro-8-hydroxyquinoline; 4-Chloro-8-quinolol; 8-Hydroxy-4-chloroquinoline; Quinolin-8-ol, 4-chloro-; 4-Chloro-8-quinolinol; 4-Cl-8-HQ
EINECS	Contact for details

Quality Control

Our 4-Chloro-8-Hydroxyquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, containers should be amber or opaque.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.