Description

(1S)-1,2,3,4,4Aβ,9,10,10Aα-Octahydro-1-Methyl-1β-Phenanthrenecarbaldehyde is a high-purity, stereochemically defined synthetic intermediate of significant interest in advanced organic synthesis. Its rigid, fused-ring phenanthrene-derived structure makes it a valuable chiral building block for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical development teams working on novel therapeutic agents, particularly in areas requiring specific stereochemical control.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel steroid analogs, terpenoid-derived compounds, and other bioactive molecules with complex polycyclic frameworks.
• Asymmetric Synthesis: Utilized as a sophisticated starting material or chiral template in catalytic asymmetric reactions to induce stereoselectivity in downstream products.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical space for drug discovery.
• Fine Chemical Synthesis: Acts as a building block for the preparation of specialty chemicals, advanced materials, and ligands for catalysis.
• Academic & Industrial R&D: Used in methodological development and the total synthesis of natural products with intricate ring systems.

Basic Information

Product Name	(1S)-1,2,3,4,4Aβ,9,10,10Aα-Octahydro-1-Methyl-1β-Phenanthrenecarbaldehyde
CAS No.	57289-39-1
Molecular Formula	C16H22O
Molecular Weight	230.35 g/mol
Synonyms	(1S)-1,2,3,4,4aβ,9,10,10aα-Octahydro-1-methyl-1β-phenanthrenecarboxaldehyde; (1S)-1-Methyl-1,2,3,4,4aβ,9,10,10aα-octahydrophenanthrene-1β-carbaldehyde; 1β-Methyl-1α-formyl-octahydrophenanthrene (stereospecific); (1S,4aS,10aR)-1-Methyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carbaldehyde; Chiral Octahydrophenanthrene Carbaldehyde; Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Our (1S)-1,2,3,4,4Aβ,9,10,10Aα-Octahydro-1-Methyl-1β-Phenanthrenecarbaldehyde is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and stereochemical composition are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.