Description

Hyaluronate Decasaccharide is a precisely defined, low molecular weight oligosaccharide derived from the controlled enzymatic or chemical depolymerization of high molecular weight hyaluronic acid. This specific 10-sugar unit fragment is valued for its enhanced bioavailability and potent biological signaling properties compared to its polymeric counterpart. It serves as a critical active ingredient and research tool in advanced cosmeceutical formulations, ophthalmology, and nutraceutical development, where its ability to modulate cellular processes is leveraged.

Application

• Advanced Skincare & Cosmeceuticals: Key active for anti-aging serums, moisturizers, and wound-healing formulations due to its deep skin penetration and ability to stimulate collagen synthesis and cellular regeneration.
• Ophthalmic Solutions: Used in eye drops and surgical viscoelastics for its lubricating, anti-inflammatory, and wound-healing properties on the ocular surface.
• Nutraceuticals & Functional Foods: Incorporated into supplements targeting joint health, skin hydration, and gastrointestinal wellness, leveraging its systemic bioavailability.
• Pharmaceutical R&D: Serves as a standard reference material and an active pharmaceutical ingredient (API) intermediate in developing therapies for osteoarthritis, wound care, and dry eye disease.
• Biomedical Research: Utilized in cell culture and molecular biology to study CD44 and RHAMM receptor interactions, inflammation pathways, and angiogenesis.
• Veterinary Medicine: Applied in joint health supplements and topical treatments for companion animals and horses.

Basic Information

Product Name	Hyaluronate Decasaccharide
CAS No.	57282-62-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Hyaluronic Acid Decasaccharide; HA10; Hyaluronan Decamer; Oligo-Hyaluronic Acid (10-mer); Sodium Hyaluronate Decasaccharide; Decasaccharide of Hyaluronate; Low Molecular Weight Hyaluronic Acid Fragment; 2-Acetamido-2-deoxy-3-O-(β-D-gluco-4-enepyranosyluronic acid)-D-glucose decamer
EINECS	Contact for details

Quality Control

Our Hyaluronate Decasaccharide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and oligosaccharide profile verification, to ensure it meets stringent specifications for pharmaceutical and cosmetic R&D. A Certificate of Analysis (COA) detailing identity, purity, and safety parameters is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0% (as Decasaccharide)
Molecular Weight Distribution	≥ 90% within target range (HPLC-SEC)
Water Content (KF)	≤ 8.0 %
Residue on Ignition	≤ 1.0 %
Heavy Metals	≤ 10 ppm
Bacterial Endotoxins	< 0.5 EU/mg (if applicable)
Microbial Enumeration	Meets Ph. Eur. 2.6.12/2.6.13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.