Description

3-Chloropyridine-2-Carboxylic Acid is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a chlorine substituent on the pyridine ring, makes it an essential intermediate for constructing complex molecules with high precision. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infective agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the pyridine core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed coupling reactions and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Integral to the multi-step synthesis of complex dyes, pigments, and other specialty chemicals.

Basic Information

Product Name	3-Chloropyridine-2-Carboxylic Acid
CAS No.	57266-69-0
Molecular Formula	C6H4ClNO2
Molecular Weight	157.55 g/mol
Synonyms	2-Carboxy-3-chloropyridine; 3-Chloro-2-pyridinecarboxylic Acid; 3-Chloropicolinic Acid; 3-Chloropyridine-2-carboxylic acid; 3-Chloro-2-pyridinylcarboxylic Acid; 3-Chloro-2-pyridylcarboxylic Acid; 3-Chloropyridine-2-carboxylate
EINECS	Contact for details

Quality Control

Our 3-Chloropyridine-2-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, and NMR to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and specific impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158°C - 162°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.