Description

2,8-Bis(Trifluoromethyl)-4-Methylquinoline is a specialized fluorinated quinoline derivative, a key building block in advanced organic synthesis. Its value lies in the unique electronic and steric properties imparted by the trifluoromethyl groups, which are crucial for developing high-performance materials and active pharmaceutical ingredients. This compound is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for creating novel molecules with enhanced stability and bioactivity.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Research: Used in developing advanced pesticides and herbicides, where the fluorine atoms contribute to improved metabolic stability and membrane permeability.
• Material Science: Acts as a monomer or functional additive in the creation of specialty polymers, liquid crystals, and organic electronic materials (OLEDs, OFETs) due to its electron-withdrawing character.
• Coordination Chemistry & Catalysis: Employed as a ligand precursor for metal complexes used in catalytic reactions, leveraging the quinoline nitrogen and fluorinated aryl groups.
• Fluorine Chemistry Research: A valuable substrate for studying nucleophilic aromatic substitution and other reactions specific to perfluoroalkylated aromatic systems.

Basic Information

Product Name	2,8-Bis(Trifluoromethyl)-4-Methylquinoline
CAS No.	57124-23-9
Molecular Formula	C₁₃H₇F₆N
Molecular Weight	291.19 g/mol
Synonyms	4-Methyl-2,8-bis(trifluoromethyl)quinoline; 2,8-Bis(trifluoromethyl)-4-methylquinoline; Quinoline, 2,8-bis(trifluoromethyl)-4-methyl-; 4-Methyl-2,8-di(trifluoromethyl)quinoline; 2,8-Bis(trifluoromethyl)-4-methyl-quinoline; 57124-23-9 (CAS); 4-Methyl-2,8-bis(trifluoromethyl)chinolin
EINECS	Contact for details

Quality Control

Our 2,8-Bis(Trifluoromethyl)-4-Methylquinoline is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity assay and GC/MS or NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.