Description

7-Chloro-4-hydroxy-2-(trifluoromethyl)quinoline is a high-value, multi-functional quinoline derivative that serves as a critical synthetic intermediate in advanced chemical manufacturing. Its unique molecular structure, featuring both chloro and trifluoromethyl substituents, provides exceptional reactivity and stability for constructing complex molecules. This compound is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting infectious diseases and central nervous system disorders.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging the bioactivity of the quinoline core.
• Material Science Precursor: Employed in the creation of specialized organic ligands and functional materials, such as metal-organic frameworks (MOFs) and OLED components.
• Chemical Research (R&D): Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fluorinated Compound Production: Acts as a starting material for introducing the trifluoromethyl group into more complex fluorinated target molecules.

Basic Information

Product Name	7-Chloro-4-hydroxy-2-(trifluoromethyl)quinoline
CAS No.	57124-20-6
Molecular Formula	C₁₀H₅ClF₃NO
Molecular Weight	247.60 g/mol
Synonyms	7-Chloro-4-hydroxy-2-(trifluoromethyl)quinoline; 2-(Trifluoromethyl)-7-chloro-4-quinolinol; 4-Hydroxy-7-chloro-2-trifluoromethylquinoline; 7-Chloro-2-trifluoromethyl-4-quinolinol; Quinoline, 7-chloro-4-hydroxy-2-(trifluoromethyl)-; 57124-20-6; 7-Chloro-4-hydroxy-2-trifluoromethylquinoline
EINECS	Contact for details

Quality Control

Every batch of 7-Chloro-4-hydroxy-2-(trifluoromethyl)quinoline is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and compliance with your project requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality protocols are designed to meet the stringent standards of pharmaceutical and agrochemical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.