Description

4-Bromo-8-Chloro-2-(Trifluoromethyl)Quinoline is a high-value, multi-functional heterocyclic building block characterized by its halogenated and trifluoromethyl-substituted quinoline core. This compound is essential for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides, leveraging the biological activity of the quinoline scaffold and halogen substituents.
• Material Science: Serves as a building block for creating organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry: The trifluoromethyl group makes it a valuable synthon for introducing fluorine atoms to enhance metabolic stability, lipophilicity, and bioavailability in final molecules.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological studies and discovery chemistry.

Basic Information

Product Name	4-Bromo-8-Chloro-2-(Trifluoromethyl)Quinoline
CAS No.	57124-18-2
Molecular Formula	C10H4BrClF3N
Molecular Weight	310.50 g/mol
Synonyms	4-Bromo-8-chloro-2-(trifluoromethyl)quinoline; 8-Chloro-4-bromo-2-(trifluoromethyl)quinoline; Quinoline, 4-bromo-8-chloro-2-(trifluoromethyl)-; 2-(Trifluoromethyl)-4-bromo-8-chloroquinoline; 4-Bromo-8-chloro-2-trifluoromethylquinoline
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-8-Chloro-2-(Trifluoromethyl)Quinoline is produced and analyzed under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.