Description

2-[2,8-Bis(Trifluoromethyl)-4-Quinolyl]Oxirane is a high-value, fluorinated heterocyclic building block with a reactive epoxide functional group. This compound is critical for introducing the unique 2,8-bis(trifluoromethyl)quinoline pharmacophore into advanced molecular architectures, imparting desirable properties like enhanced metabolic stability and lipophilicity. It is primarily sought by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of new drug candidates, particularly in areas targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in creating advanced active ingredients for crop protection, where the fluorine atoms and quinoline core can contribute to improved efficacy and environmental profile.
• Material Science Research: Serves as a precursor for synthesizing specialty polymers, liquid crystals, or organic electronic materials that benefit from fluorinated components.
• Chemical Biology Probes: Utilized in developing fluorescent tags or molecular probes due to the inherent photophysical properties of the quinoline scaffold.
• Scale-up & Process Chemistry: Supplied for route scouting, optimization, and pilot-scale production of target molecules in commercial pipelines.

Basic Information

Product Name	2-[2,8-Bis(Trifluoromethyl)-4-Quinolyl]Oxirane
CAS No.	57120-54-4
Molecular Formula	C₁₄H₇F₆NO
Molecular Weight	319.21 g/mol
Synonyms	4-(Oxiran-2-yl)-2,8-bis(trifluoromethyl)quinoline; 2,8-Bis(trifluoromethyl)-4-(oxiranyl)quinoline; 2-(2,8-Bis(trifluoromethyl)quinolin-4-yl)oxirane; 4-(2,8-Bis(trifluoromethyl)-4-quinolyl)oxirane; 2,8-Bis(trifluoromethyl)-4-vinylquinoline epoxide; (2,8-Bis(trifluoromethyl)quinolin-4-yl)oxirane; Quinoline, 2,8-bis(trifluoromethyl)-4-(oxiranylmethyl)-
EINECS	Contact for details

Quality Control

Every batch of 2-[2,8-Bis(Trifluoromethyl)-4-Quinolyl]Oxirane is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical R&D and scale-up activities. A detailed Certificate of Analysis (COA) including HPLC purity, NMR, and MS confirmation is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive compound from degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.