Description

1,2,3,7,8-Pentachlorodibenzofuran is a specific, high-purity congener of the polychlorinated dibenzofuran (PCDF) family, a class of compounds of significant environmental and analytical interest. This compound is primarily utilized as a critical reference standard and analytical standard for precise identification and quantification in complex matrices. It is essential for researchers, analytical laboratories, and regulatory bodies involved in environmental monitoring, food safety, and toxicological studies. The availability of a well-characterized standard is fundamental for ensuring data accuracy in the analysis of persistent organic pollutants (POPs).

Application

• Analytical Reference Standard: Primary use for the calibration of GC-MS, HRGC/HRMS, and other analytical instruments for the detection of dioxin-like compounds.
• Environmental Analysis: Critical for testing soil, sediment, water, and air samples for contamination by polychlorinated dibenzofurans as per EPA and other international methods.
• Food and Feed Safety Testing: Used in the quantification of PCDFs in foodstuffs, animal feed, and edible oils to ensure compliance with strict EU and global regulatory limits.
• Toxicological Research: Serves as a pure congener for studying the specific toxicokinetics, metabolism, and health effects of 1,2,3,7,8-PeCDF.
• Quality Control and Method Validation: Employed by testing laboratories and manufacturers to validate analytical procedures and ensure the reliability of internal quality control programs.
• Regulatory Compliance and Proficiency Testing: Essential for laboratories participating in inter-laboratory comparison studies and demonstrating competency for accreditation (e.g., ISO/IEC 17025).

Basic Information

Product Name	1,2,3,7,8-Pentachlorodibenzofuran
CAS No.	57117-41-6
Molecular Formula	C₁₂H₃Cl₅O
Molecular Weight	340.40 g/mol
Synonyms	1,2,3,7,8-PeCDF; PeCDF (1,2,3,7,8-); 1,2,3,7,8-Pentachlorodibenzo[b,d]furan; Dibenzofuran, 1,2,3,7,8-pentachloro-; 2,3,4,7,8-Pentachlorodibenzofuran (isomer); PCBDF (congener); Polychlorinated dibenzofuran congener # 105 (IUPAC numbering scheme).
EINECS	Contact for details

Quality Control

Every batch of our 1,2,3,7,8-Pentachlorodibenzofuran is produced and handled under strict quality protocols to ensure identity, purity, and stability. Comprehensive analysis is performed using state-of-the-art techniques including gas chromatography (GC) and mass spectrometry (MS). We provide a detailed Certificate of Analysis (COA) with each shipment, which includes batch-specific data on purity, solvent content, and confirmatory identification. Our quality system supports compliance with the standards required for analytical reference materials and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C (refrigerated) or as indicated on the label or Certificate of Analysis. For long-term storage, solutions should be kept at -20°C under inert atmosphere. Allow the product to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid / Solution in nonane, toluene, or DMSO
Identification (IR / MS)	Conforms to reference spectrum
Purity (GC)	≥ 98.0% (typical ≥ 99.0%)
Purity (HPLC)	≥ 98.0%
Concentration (for solutions)	10 µg/mL, 50 µg/mL, or custom (in specified solvent)
Solvent (for solutions)	Nonane, Toluene, Isooctane, DMSO
Related Substances (HPLC/GC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 2.0%
Water Content (K.F.)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.