Description

12-Hydroxybenzo[A]Pyrene is a hydroxylated derivative of the polycyclic aromatic hydrocarbon benzo[a]pyrene. This compound is of significant interest in research and analytical chemistry, particularly as a key metabolite and biomarker for exposure studies. It serves as a critical reference standard for laboratories in the environmental, toxicological, and life science sectors requiring precise analytical calibration.

Application

• Analytical Reference Standard: Primary use as a high-purity certified standard for HPLC, GC-MS, and LC-MS analysis in environmental and biological monitoring.
• Metabolite Research: Essential for studying the metabolic pathways, bioactivation, and detoxification of benzo[a]pyrene in toxicological research.
• Biomarker Development: Used in the development and validation of analytical methods to detect and quantify human exposure to PAHs (Polycyclic Aromatic Hydrocarbons).
• Environmental Analysis: Calibration standard for testing PAH contamination in soil, water, air particulates, and food products.
• Biochemical Research: Tool compound for investigating DNA adduct formation and the mechanisms of PAH-induced carcinogenicity.
• Quality Control: Serves as an internal or external standard in laboratory quality control protocols to ensure analytical accuracy and reproducibility.

Basic Information

Product Name	12-Hydroxybenzo[A]Pyrene
CAS No.	56892-33-2
Molecular Formula	C₂₀H₁₂O
Molecular Weight	268.31 g/mol
Synonyms	12-Hydroxybenzo[a]pyrene; 12-Hydroxy-BaP; 12-OH-BaP; Benzo[a]pyren-12-ol; 12-Hydroxy-3,4-benzpyrene; 12-HBP; 1-Hydroxypyrene (Note: This is a different isomer, often searched in context); PAH Metabolite Standard
EINECS	Contact for details

Quality Control

Every batch of 12-Hydroxybenzo[A]Pyrene is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical documentation to support your research and regulatory needs. Certificates of Analysis (COA) detailing purity, identity confirmation, and impurity profiles are available for each lot. Our quality commitment ensures consistency and reliability for your critical analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light). For long-term storage, consider storing desiccated under inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to pale yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.