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10-Hydroxybenzo[A]Pyrene CAS NO 56892-31-0
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CAS No.:56892-31-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
10-Hydroxybenzo[A]Pyrene is a hydroxylated derivative of the polycyclic aromatic hydrocarbon benzo[a]pyrene, a compound of significant research interest. This specific metabolite is crucial for studying the environmental fate, metabolic pathways, and toxicological profiles of its parent compound. It serves as a vital reference standard and analytical intermediate for researchers and quality control laboratories in environmental monitoring, toxicology, and analytical chemistry.
Application
- Analytical Reference Standard: Primary use as a high-purity certified standard for calibrating equipment and quantifying benzo[a]pyrene metabolites in complex matrices.
- Environmental Research: Used in studies to track the biodegradation, transformation, and persistence of polycyclic aromatic hydrocarbons (PAHs) in soil and water systems.
- Metabolic Pathway Studies: Essential for investigating the phase I and phase II metabolism of benzo[a]pyrene in biological systems, crucial for toxicological assessments.
- Biomarker Development: Acts as a key compound in developing and validating analytical methods for detecting PAH exposure biomarkers in human and animal studies.
- Toxicology & Carcinogenesis Research: Employed in mechanistic studies to understand the role of specific metabolites in the carcinogenic potential of PAHs.
- Pharmaceutical Impurity Profiling: May be used as a trace impurity standard in the analysis of certain synthetic compounds or in environmental risk assessments for pharmaceuticals.
Basic Information
| Item | Detail |
|---|---|
| Product Name | 10-Hydroxybenzo[A]Pyrene |
| CAS No. | 56892-31-0 |
| Molecular Formula | C₂₀H₁₂O |
| Molecular Weight | 268.31 g/mol |
| Synonyms | 10-Hydroxybenzo(a)pyrene; 10-Hydroxy-BaP; 10-OH-BaP; Benzo[a]pyren-10-ol; 10-HBP; 10-Hydroxy-3,4-benzpyrene; 10-Hydroxy-3,4-benzopyrene |
| EINECS | Contact for details |
Quality Control
Every batch of 10-Hydroxybenzo[A]Pyrene is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards for reference materials. Comprehensive analysis includes HPLC for purity, spectroscopic methods for identification, and residual solvent screening. Certificates of Analysis (COA) detailing all test results and specifications are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light). For long-term storage, consider storage under inert atmosphere at lower temperatures (-20°C) to ensure maximum stability.
Specification
| Item | Specification |
|---|---|
| Appearance | Off-white to light yellow powder or crystals |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Purity (HPLC) | ≥ 98.0% |
| Related Substances (HPLC) | Total impurities ≤ 2.0% |
| Loss on Drying | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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