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2-Azido-2-Deoxy-D-Glucose CAS NO 56883-39-7
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CAS No.:56883-39-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Azido-2-Deoxy-D-Glucose is a chemically modified glucose analog where the hydroxyl group at the C-2 position is replaced by an azido functional group. This structural modification makes it a valuable biochemical tool for metabolic studies and click chemistry applications. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical development, and chemical synthesis sectors.
Application
- Metabolic Probe: Used to study glucose uptake and metabolism in cells, particularly in cancer research where altered glucose metabolism is a hallmark.
- Click Chemistry Reagent: Serves as a bioorthogonal handle for Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, enabling the labeling and visualization of glycans and other biomolecules.
- Glycobiology Research: Acts as a precursor for the synthesis of azido-labeled glycoconjugates and metabolic glycoengineering studies.
- Pharmaceutical Intermediate: Employed in the research and development of novel therapeutic agents, including antiviral and anticancer compounds.
- Bioconjugation: Facilitates the site-specific attachment of drugs, dyes, or other molecules to proteins, antibodies, or nanoparticles.
- Diagnostic Agent Development: Investigated for potential use in developing imaging probes for positron emission tomography (PET) and other modalities.
Basic Information
| Product Name | 2-Azido-2-Deoxy-D-Glucose |
| CAS No. | 56883-39-7 |
| Molecular Formula | C6H11N3O5 |
| Molecular Weight | 205.17 g/mol |
| Synonyms | 2-Azido-2-deoxyglucose; 2-Azido-2-deoxy-D-glucose; 2-Azido-2-desoxy-D-glucose; 2-Azido-2-deoxy-D-glucopyranose; 2-Azido-2-deoxy-D-hexose; D-Glucose, 2-azido-2-deoxy-; 2-N3-2-dGlc |
| EINECS | Contact for details |
Quality Control
Our 2-Azido-2-Deoxy-D-Glucose is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic nature, the container should be kept tightly sealed in a desiccated environment to prevent moisture absorption.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 2.0% |
| Residue on Ignition | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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