Description

(S)-4-[(Methoxymethyl)Phosphinyl]-2-[(Trifluoroacetyl)Amino]Butanoic Acid Methyl Ester is a high-purity, chiral organophosphorus compound that serves as a critical synthetic intermediate. Its value lies in its defined stereochemistry and functional groups, enabling precise chemical transformations in advanced synthesis. This product is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of chiral drug candidates, particularly those targeting neurological or metabolic pathways.
• Agrochemical Research: Used in developing advanced herbicides, insecticides, or plant growth regulators with specific stereochemical requirements.
• Chemical Biology Probe: Serves as a precursor for labeled compounds or activity-based probes to study enzyme function and inhibition.
• Peptidomimetic Synthesis: Incorporated into the backbone of peptide analogs to enhance stability, bioavailability, or receptor binding affinity.
• Catalyst Ligand Development: Potential precursor for chiral ligands used in asymmetric catalysis for producing enantiomerically pure compounds.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke molecules for clinical trials or specialty chemical applications.

Basic Information

Product Name	(S)-4-[(Methoxymethyl)Phosphinyl]-2-[(Trifluoroacetyl)Amino]Butanoic Acid Methyl Ester
CAS No.	56772-24-8
Molecular Formula	C9H15F3NO6P
Molecular Weight	321.19 g/mol
Synonyms	Methyl (2S)-4-(Methoxymethylphosphinyl)-2-[(trifluoroacetyl)amino]butanoate; (S)-Methyl 4-(Methoxymethylphosphinyl)-2-(trifluoroacetamido)butanoate; (S)-4-(Methoxymethylphosphinyl)-2-(trifluoroacetamido)butyric Acid Methyl Ester; Phosphinothricin Trifluoroacetyl Methyl Ester (S-isomer); S-Isomer of Methyl 2-(Trifluoroacetamido)-4-(methoxymethylphosphinyl)butyrate; L-Phosphinothricin Trifluoroacetyl Methyl Ester Derivative; (S)-Configuration TFA-Protected Phosphinothricin Methyl Ester
EINECS	Contact for details

Quality Control

Our (S)-4-[(Methoxymethyl)Phosphinyl]-2-[(Trifluoroacetyl)Amino]Butanoic Acid Methyl Ester is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (S-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.