Description

4-Diazo-3-Phenylisoxazol-5(4H)-One is a specialized diazo compound with a reactive isoxazolone core, serving as a versatile intermediate in advanced organic synthesis. Its value lies in its ability to act as a precursor for generating carbenes or as a coupling agent, facilitating the construction of complex heterocyclic and pharmaceutical scaffolds. This high-purity chemical is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those containing isoxazole or other nitrogen-rich heterocycles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require specific, reactive diazo functionalities.
• Material Science: Potential precursor for photoactive polymers or as a cross-linking agent in specialty polymer formulations.
• Organic Synthesis Reagent: Employed in cycloaddition reactions and as a source of carbenes for C-H insertion and other transformative organic reactions.
• Dye & Pigment Intermediate: Can be utilized in the synthesis of advanced colorants and photochromic materials.
• Academic & Industrial R&D: Serves as a critical reagent for methodological development and exploring new chemical spaces in laboratory settings.

Basic Information

Product Name	4-Diazo-3-Phenylisoxazol-5(4H)-One
CAS No.	56666-67-2
Molecular Formula	C9H5N3O2
Molecular Weight	187.16 g/mol
Synonyms	5(4H)-Isoxazolone, 4-diazo-3-phenyl-; 3-Phenyl-4-diazo-5-isoxazolone; 4-Diazo-3-phenyl-2-isoxazolin-5-one; 4-Diazo-3-phenylisoxazol-5-one; 4-Diazo-3-phenyl-δ²-isoxazolin-5-one; Diazo Phenyl Isoxazolone; DPI
EINECS	Contact for details

Quality Control

Our 4-Diazo-3-Phenylisoxazol-5(4H)-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and industrial applications. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) is supplied with each shipment to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive nature, containers should be kept in opaque or amber packaging. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.