Description

(3As)-3A,4,4Aβ,7,8,8A,9,9Aβ-Octahydro-5,8Aα-Dimethyl-3-Methylenenaphtho[2,3-B]Furan-2(3H)-One is a complex sesquiterpene lactone derivative, a class of compounds known for their significant biological activity and utility in advanced organic synthesis. This high-purity intermediate is valued for its unique stereochemistry and functional groups, which make it a critical building block for pharmaceutical research and fine chemical manufacturing. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and complex natural product analogs.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of potential therapeutic agents, particularly in oncology and anti-inflammatory drug discovery.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its complex ring system for bioactivity.
• Natural Product Analog Synthesis: Acts as a core scaffold for the semi-synthesis or total synthesis of complex natural products and their derivatives for biological screening.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development of new stereoselective catalytic reactions.
• Fine Chemical Production: Utilized in the manufacture of high-value, low-volume specialty chemicals for advanced material science applications.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Details
Product Name	(3As)-3A,4,4Aβ,7,8,8A,9,9Aβ-Octahydro-5,8Aα-Dimethyl-3-Methylenenaphtho[2,3-B]Furan-2(3H)-One
CAS No.	56632-84-9
Molecular Formula	C₁₅H₂₀O₂
Molecular Weight	232.32 g/mol
Synonyms	Alantolactone Isomer; Isoalantolactone (specific stereoisomer); (3aR,4S,8aS,9aR)-3a,4,4a,7,8,8a,9,9a-Octahydro-5,8a-dimethyl-3-methylene-naphtho[2,3-b]furan-2(3H)-one; Helenin (related mixture); Inula camphor derivative; Elecampane camphor isomer; 5,8a-Dimethyl-3-methylenenaphtho[2,3-b]furan-2(3H)-one, octahydro-
EINECS	Contact for details

Quality Control

Our (3As)-3A,4,4Aβ,7,8,8A,9,9Aβ-Octahydro-5,8Aα-Dimethyl-3-Methylenenaphtho[2(3H)-One is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. We can support development projects with custom purity grades and analytical data packages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere if opened, to prevent potential degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.