Description

Alanine, n-Methyl-, Ethyl Ester (9Ci) is a protected amino acid derivative, specifically the ethyl ester of N-methylalanine. This compound is a versatile and valuable chiral building block in organic synthesis, prized for its role in introducing the N-methylalanine moiety into more complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of peptides, peptidomimetics, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in peptide-based drug discovery.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate the N-methylalanine residue, which can enhance metabolic stability and alter conformational properties of peptide chains.
• Agrochemical Research: Serves as a building block in the synthesis of advanced crop protection agents and herbicides that utilize amino acid frameworks.
• Biochemical Research: Employed in studies of enzyme inhibition, receptor-ligand interactions, and as a standard or reagent in analytical method development.
• Fine Chemical Synthesis: Utilized in the preparation of specialty chemicals, catalysts, and ligands for asymmetric synthesis.

Basic Information

Product Name	Alanine, n-Methyl-, Ethyl Ester (9Ci)
CAS No.	56428-90-1
Molecular Formula	C6H13NO2
Molecular Weight	131.17 g/mol
Synonyms	Ethyl N-Methylalaninate; N-Methylalanine Ethyl Ester; L-N-Methylalanine ethyl ester; (S)-2-(Methylamino)propanoic acid ethyl ester; Alanine, N-methyl-, ethyl ester; Ethyl 2-(methylamino)propanoate; 56428-90-1; NSC 163063
EINECS	Contact for details

Quality Control

Our Alanine, n-Methyl-, Ethyl Ester (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) providing specifications for identity, purity, and related substances is available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.