Description

(-)-11-Nor-9-Carboxy-Delta9-THC is a primary, stable carboxylic acid metabolite of δ-9-Tetrahydrocannabinol (THC). This compound is of critical importance as a definitive analytical reference standard and biomarker in forensic, clinical, and workplace drug testing. It is essential for laboratories requiring precise calibration and validation of analytical methods, such as HPLC and GC-MS, to ensure accurate detection and quantification. The high-purity material is primarily targeted at manufacturers of diagnostic kits, forensic science institutions, and clinical research organizations focused on toxicology and cannabinoid metabolism studies.

Application

• Forensic Toxicology Reference Standard: Primary application for the calibration and validation of equipment (GC-MS, LC-MS/MS) used in law enforcement and post-mortem analysis.
• Clinical Diagnostic Assay Development: Critical component in the manufacturing of ELISA kits and other immunoassays for detecting THC exposure in urine and other biological matrices.
• Workplace Drug Testing: Used as a certified reference material (CRM) to ensure the accuracy and legal defensibility of employee screening programs.
• Pharmacokinetic & Metabolic Research: Serves as a key analyte in academic and pharmaceutical research studying the absorption, distribution, metabolism, and excretion (ADME) of cannabinoids.
• Quality Control for Clinical Laboratories: Employed as an internal standard and control material to maintain the precision and reliability of routine testing procedures.
• Method Development and Validation: Essential for laboratories establishing new analytical protocols to meet regulatory guidelines (e.g., SAMHSA, ISO/IEC 17025).

Basic Information

Product Name	(-)-11-Nor-9-Carboxy-Delta9-THC
CAS No.	56354-06-4
Molecular Formula	C₂₁H₂₈O₄
Molecular Weight	344.45 g/mol
Synonyms	11-Nor-9-carboxy-δ⁹-THC; THC-COOH; 11-Nor-δ⁹-tetrahydrocannabinol-9-carboxylic acid; δ⁹-THC-11-oic acid; 11-Nor-9-carboxy-δ-9-tetrahydrocannabinol; Carboxy-THC; Major THC Metabolite; 1,3-Benzenediol, 5-pentyl-2-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-, 2-carboxy-
EINECS	Contact for details

Quality Control

Our (-)-11-Nor-9-Carboxy-Delta9-THC is manufactured and handled under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, MS), to ensure it meets the exacting standards required for forensic and diagnostic applications. Comprehensive Certificates of Analysis (COA) detailing batch-specific results are provided. We support compliance with relevant guidelines, and specifications can be aligned with user requirements for method validation.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0% (Area Percent)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.