Description

n-Propyl-n-(3-Carboxypropyl)Nitrosamine is a specialized nitrosamine compound of significant interest in chemical research and development. This compound serves as a critical intermediate and reference standard in analytical chemistry, particularly for the study of nitrosamine formation, detection, and mitigation. It is primarily utilized by research institutions, analytical laboratories, and pharmaceutical development teams focused on impurity profiling, method validation, and regulatory compliance. Its defined structure makes it essential for calibrating sensitive detection equipment and ensuring product safety in various industrial sectors.

Application

• Analytical Reference Standard: Used as a certified standard for the accurate quantification of nitrosamine impurities via HPLC, LC-MS, and GC-MS in pharmaceuticals, food, and consumer products.
• Pharmaceutical Research: Employed in studies investigating nitrosamine formation pathways, genotoxicity, and the development of robust control strategies in API synthesis and drug formulation.
• Method Development & Validation: Critical for developing, qualifying, and validating analytical methods to meet stringent regulatory requirements from agencies like the FDA and EMA.
• Chemical Synthesis Intermediate: Acts as a building block or precursor in organic synthesis for specialized research molecules within academic and industrial R&D settings.
• Quality Control & Assurance: Supports in-house QC laboratories in monitoring and controlling nitrosamine levels to ensure batch-to-batch consistency and product safety.
• Toxicological Studies: Used in environmental and health safety research to understand the metabolic fate and carcinogenic potential of nitrosamine compounds.

Basic Information

Product Name	n-Propyl-n-(3-Carboxypropyl)Nitrosamine
CAS No.	56316-37-1
Molecular Formula	C7H14N2O3
Molecular Weight	174.20 g/mol
Synonyms	N-Nitroso-N-propyl-4-aminobutyric acid; 4-(N-Nitroso-N-propylamino)butyric acid; N-Nitroso-N-propyl-γ-aminobutyric acid; N-Nitroso-N-propyl-GABA; NPNABA; N-Nitroso-N-propyl-4-aminobutanoic acid; N-Propyl-N-(3-carboxypropyl)nitrosamine; PNCN
EINECS	Contact for details

Quality Control

Every batch of n-Propyl-n-(3-Carboxypropyl)Nitrosamine is manufactured and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic techniques, to ensure compliance with industry standards for reference materials. Comprehensive Certificates of Analysis (COA) detailing batch-specific results for assay, purity, and identification are available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere for long-term stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.