Description

(+/-)-α-Methoxy-α-Trifluoromethylphenylacetic Acid CAS NO 56135-03-6 is a high-purity chiral derivatizing agent and a key synthetic intermediate in organic chemistry. Its value lies in its ability to resolve enantiomers and introduce the trifluoromethyl group, a critical moiety for modulating the biological activity and physicochemical properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for complex synthesis.

Application

• Chiral Resolution Agent: Widely used as a derivatizing reagent for the NMR and HPLC analysis of enantiomeric purity of amines, alcohols, and other chiral compounds.
• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing the pharmacologically important trifluoromethyl group.
• Agrochemical Synthesis: Employed in the research and production of advanced herbicides, fungicides, and pesticides where the CF3 group enhances efficacy and environmental stability.
• Ligand and Catalyst Preparation: Used in the development of chiral ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Acts as a precursor for fluorinated polymers and advanced organic materials with unique properties.
• Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in regulatory and R&D laboratories.

Basic Information

Product Name	(+/-)-α-Methoxy-α-Trifluoromethylphenylacetic Acid
CAS No.	56135-03-6
Molecular Formula	C11H9F3O3
Molecular Weight	246.18 g/mol
Synonyms	MTPA; α-Methoxy-α-(trifluoromethyl)phenylacetic acid; (±)-MTPA; DL-MTPA; Mosher's Acid; 2-Methoxy-2-(trifluoromethyl)phenylacetic acid; 2-Methoxy-2-(trifluoromethyl)benzenacetic acid; 2-Methoxy-2-(trifluoromethyl)phenylacetic acid
EINECS	Contact for details

Quality Control

Our (+/-)-α-Methoxy-α-Trifluoromethylphenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	64 - 68 °C
Loss on Drying	≤ 1.0 %
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.