Description

(E)-1-[(1R,4S)-6,7,7-Trimethyl-2,3-Dioxabicyclo[2.2.2]Oct-5-En-1α-Yl]-2-Buten-1-One is a high-purity, chiral bicyclic enone derivative with a complex, rigid molecular framework. This compound is valued for its role as a key chiral building block and synthetic intermediate in advanced organic synthesis, particularly for constructing molecules with specific three-dimensional architectures. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for developing novel active ingredients and complex natural product analogs.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders.
• Asymmetric Synthesis: Utilized as a building block in catalytic asymmetric reactions to introduce stereochemical complexity into target molecules.
• Fragrance & Flavor Chemistry: Acts as an intermediate for creating novel odorants and flavorants with unique olfactory properties derived from its bicyclic structure.
• Agrochemical Research: Employed in the development of new, stereospecific pesticides and herbicides where the specific spatial orientation of the molecule is crucial for bioactivity.
• Material Science Research: Investigated as a monomer or cross-linking agent for producing polymers with specialized thermal or optical properties.
• Academic & R&D Laboratories: Used in methodological studies and total synthesis projects to explore new chemical transformations and reaction pathways.

Basic Information

Product Name	(E)-1-[(1R,4S)-6,7,7-Trimethyl-2,3-Dioxabicyclo[2.2.2]Oct-5-En-1α-Yl]-2-Buten-1-One
CAS No.	56083-37-5
Molecular Formula	C₁₃H₁₈O₃
Molecular Weight	222.28 g/mol
Synonyms	(1R,4S)-6,7,7-Trimethyl-2,3-dioxabicyclo[2.2.2]oct-5-en-1-yl (2E)-but-2-en-1-one; (E)-1-[(1R,4S)-6,7,7-Trimethyl-2,3-dioxabicyclo[2.2.2]oct-5-en-1-yl]but-2-en-1-one; (1R,4S)-1-[(1E)-1-Oxo-2-buten-1-yl]-6,7,7-trimethyl-2,3-dioxabicyclo[2.2.2]oct-5-ene; Bicyclic enone derivative CAS 56083-37-5; Trimethyl dioxabicyclooctenyl butenone
EINECS	Contact for details

Quality Control

Our production of (E)-1-[(1R,4S)-6,7,7-Trimethyl-2,3-Dioxabicyclo[2.2.2]Oct-5-En-1α-Yl]-2-Buten-1-One adheres to stringent GMP-like guidelines to ensure batch-to-batch consistency and high chiral purity. Every lot is characterized using advanced analytical techniques including HPLC, GC, Chiral HPLC, and NMR to confirm identity, purity, and enantiomeric excess. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.