Description

1,3-Dioxolane, 4-Ethynyl-2,2-Dimethyl-, (4S)- (9Ci) is a chiral, high-purity chemical intermediate featuring a protected alkyne functional group within a dioxolane ring system. This compound matters for its role as a sophisticated building block in the synthesis of complex, optically active molecules, enabling precise stereochemical control. It is primarily needed by research and development teams in the pharmaceutical and advanced agrochemical sectors for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the production of advanced, stereospecific pesticides and herbicides where the specific spatial orientation of the molecule is critical for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chiral ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of novel polymers and advanced organic materials with tailored properties, leveraging its reactive alkyne group.
• Academic & Industrial R&D: A valuable reagent for synthetic organic chemists in universities and corporate labs exploring new reaction methodologies and complex natural product synthesis.

Basic Information

Product Name	1,3-Dioxolane, 4-Ethynyl-2,2-Dimethyl-, (4S)- (9Ci)
CAS No.	56017-85-7
Molecular Formula	C7H10O2
Molecular Weight	126.15 g/mol
Synonyms	(4S)-4-Ethynyl-2,2-dimethyl-1,3-dioxolane; (S)-4-Ethynyl-2,2-dimethyl-1,3-dioxolane; 4-Ethynyl-2,2-dimethyl-1,3-dioxolane, (4S)-; (S)-2,2-Dimethyl-4-ethynyl-1,3-dioxolane; (S)-4-Ethynyl-2,2-dimethyl-[1,3]dioxolane; Chiral ethynyl dioxolane; (S)-Acetonide of 3-butyn-1,2-diol
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolane, 4-Ethynyl-2,2-Dimethyl-, (4S)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC and GC, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.