Description

(5R)-5,6,7,8-Tetrahydro-6β,7α-Dimethyl-5-(3,4,5-Trimethoxyphenyl)Naphtho[2,3-D]-1,3-Dioxole CAS NO 55924-17-9 is a high-purity, complex organic intermediate characterized by its specific stereochemistry and naphthodioxole core structure. This compound is of significant value for its role as a key building block in advanced pharmaceutical synthesis and fine chemical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of potential therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery programs.
• Agrochemical Research: Used in the development of novel, high-efficacy active ingredients for crop protection, leveraging its complex polycyclic structure.
• Fine Chemical Synthesis: Acts as a versatile scaffold for creating specialty chemicals, dyes, and advanced materials requiring specific stereochemical configurations.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in asymmetric synthesis and heterocyclic chemistry.
• Process Chemistry Development: Utilized for scaling up and optimizing synthetic routes for target molecules in pilot plant and manufacturing settings.

Basic Information

Product Name	(5R)-5,6,7,8-Tetrahydro-6β,7α-Dimethyl-5-(3,4,5-Trimethoxyphenyl)Naphtho[2,3-D]-1,3-Dioxole
CAS No.	55924-17-9
Molecular Formula	C24H28O5
Molecular Weight	396.48 g/mol
Synonyms	(5R)-5,6,7,8-Tetrahydro-6,7-dimethyl-5-(3,4,5-trimethoxyphenyl)naphtho[2,3-d][1,3]dioxole; (6bR,7aS)-5,6,7,8-Tetrahydro-6b,7-dimethyl-5-(3,4,5-trimethoxyphenyl)naphtho[2,3-d][1,3]dioxole; NSC 339586; 1,3-Dioxolo[4,5-j]naphtho[2,3-b]pyran Derivative; Tetrahydrodimethyltrimethoxyphenylnaphthodioxole
EINECS	Contact for details

Quality Control

Our (5R)-5,6,7,8-Tetrahydro-6β,7α-Dimethyl-5-(3,4,5-Trimethoxyphenyl)Naphtho[2,3-D]-1,3-Dioxole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure consistency and compliance with client specifications and cGMP guidelines where applicable. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.