Description

Boc-Lys(Ac)-OH HCl is a protected amino acid derivative, specifically an Nα-Boc and Nε-acetyl protected L-lysine hydrochloride salt. This compound is a crucial building block in solid-phase peptide synthesis (SPPS), enabling the controlled incorporation of modified lysine residues. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel peptides, peptidomimetics, and bioconjugates.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled introduction of acetylated lysine residues into peptide chains.
• Bioconjugation & Linker Chemistry: Serves as a precursor for creating functionalized peptides with specific reactive handles via its free carboxyl group.
• Pharmaceutical Research: Used in the development of therapeutic peptides targeting various diseases, where post-translational modifications like acetylation are critical for bioactivity.
• Biochemical Tool Development: Employed in the synthesis of substrates and inhibitors for enzymes like histone deacetylases (HDACs) and acetyltransferases.
• Material Science: A building block for creating functionalized polymers and biomaterials with peptide motifs.

Basic Information

Product Name	Boc-Lys(Ac)-OH HCl
CAS No.	55757-60-3
Molecular Formula	C13H25ClN2O5
Molecular Weight	324.80 g/mol
Synonyms	Nα-Boc-Nε-acetyl-L-lysine hydrochloride; Boc-Lys(Ac)-OH·HCl; (2S)-6-Acetamido-2-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoic acid hydrochloride; Nα-(tert-Butoxycarbonyl)-Nε-acetyl-L-lysine hydrochloride; Boc-Lys(Ac)-OH hydrochloride; Ac-Lys(Boc)-OH·HCl; Boc-Lys(Ac)-OH monohydrochloride
EINECS	Contact for details

Quality Control

Our Boc-Lys(Ac)-OH HCl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and NMR for structural confirmation. A Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with every shipment to ensure compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.