Description

α-Linolenic Anhydride is a specialized chemical derivative of the essential ω-3 fatty acid, α-linolenic acid (ALA). This compound serves as a versatile and reactive intermediate, enabling the controlled introduction of the ALA moiety into more complex molecular structures. It is particularly valuable for researchers and manufacturers in the pharmaceutical, nutraceutical, and advanced materials sectors seeking to develop or enhance products with specific lipid-based functionalities. Its utility stems from the anhydride group's reactivity, which facilitates efficient synthesis under milder conditions.

Application

• Pharmaceutical Intermediate: Used in the synthesis of prodrugs, lipid conjugates, and novel active pharmaceutical ingredients (APIs) targeting metabolic and inflammatory pathways.
• Nutraceutical & Cosmetic Ingredient Synthesis: Serves as a key building block for creating stabilized, bioavailable derivatives of ω-3 fatty acids for dietary supplements and high-end skincare formulations.
• Polymer & Material Science: Employed in the production of specialty polymers, resins, and surface-modifying agents to impart hydrophobicity, flexibility, or specific biorelevant properties.
• Biochemical Research: Acts as a crucial reagent for studying lipid metabolism, enzyme activity, and for the chemical modification of proteins or peptides to alter their function or stability.
• Lipid Nanoparticle (LNP) Formulation: Investigated for use in the development of advanced drug delivery systems, including LNPs for mRNA and other nucleic acid therapeutics.

Basic Information

Product Name	α-Linolenic Anhydride
CAS No.	55726-27-7
Molecular Formula	C36H58O5
Molecular Weight	570.85 g/mol
Synonyms	9,12,15-Octadecatrienoic Anhydride; Linolenic Anhydride; (9Z,12Z,15Z)-9,12,15-Octadecatrienoic Acid Anhydride; ALA Anhydride; ω-3 Fatty Acid Anhydride; all-cis-9,12,15-Octadecatrienoic Acid Anhydride
EINECS	Contact for details

Quality Control

Our α-Linolenic Anhydride is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity assessment and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing specific results for purity, residual solvents, and other critical parameters is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and maintain product integrity.

Specification

Item	Specification
Appearance	Clear, pale yellow to yellow viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Acid Value	≤ 5.0 mg KOH/g
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.