Description

n-Acetyl-2-o-Methyl-β-Neuraminic Acid 9-Acetate is a chemically modified derivative of sialic acid, a critical carbohydrate moiety in glycobiology. This compound is essential for advanced research and development in the synthesis of complex glycoconjugates and glycomimetics. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly in the development of novel therapeutics, diagnostic tools, and vaccine components targeting sialic acid-mediated biological pathways.

Application

• Glycoconjugate Synthesis: A key intermediate for the chemical and enzymatic synthesis of complex oligosaccharides and glycoproteins.
• Pharmaceutical Research: Used in the development of sialidase inhibitors, anti-influenza drugs, and other therapeutics that target sialic acid-binding proteins.
• Biochemical Tool Development: Serves as a substrate or inhibitor in enzymatic assays to study sialyltransferases, neuraminidases, and other glycan-processing enzymes.
• Vaccine Adjuvant Research: Investigated for its potential role in modulating immune responses as part of conjugate vaccine platforms.
• Diagnostic Reagent Production: Employed in the manufacture of reagents for detecting pathogens or cellular markers that interact with sialic acids.
• Glycomimetic Drug Design: A building block for creating stable analogs of natural sialosides with enhanced pharmacological properties.

Basic Information

Product Name	n-Acetyl-2-o-Methyl-β-Neuraminic Acid 9-Acetate
CAS No.	55717-57-2
Molecular Formula	C15H23NO10
Molecular Weight	377.34 g/mol
Synonyms	5-Acetamido-2,4-dideoxy-2,4-bis-O-methyl-3,5,9-trideoxy-D-glycero-D-galacto-non-2-ulopyranosonic Acid 9-Acetate; 9-O-Acetyl-N-acetyl-2-O-methylneuraminic Acid; Methylated Sialic Acid Derivative; 2-O-Methyl-N-acetylneuraminic Acid 9-Acetate; N-Acetyl-9-O-acetyl-2-O-methylneuraminate
EINECS	Contact for details

Quality Control

Our n-Acetyl-2-o-Methyl-β-Neuraminic Acid 9-Acetate is produced under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. While not certified to a specific pharmacopeial monograph (USP/EP), our quality system ensures the material meets the stringent requirements for advanced biochemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.