Description

(-)-3-Hydroxy-4-(Tetrahydro-2,6,6-Trimethyl-2H-Pyran-2-Yl)Benzoic Acid is a high-purity chiral intermediate of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring a benzoic acid core substituted with a hydroxy group and a tetramethyltetrahydropyran moiety, makes it a valuable building block for creating complex, optically active molecules. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries seeking to develop novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, particularly in therapeutic areas requiring high stereochemical purity.
• Fine Chemical Synthesis: Used as a sophisticated building block for constructing complex natural product analogs and specialty organic compounds.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development and testing of new chiral catalysts and synthetic methodologies.
• Agrochemical Development: Employed in the research phase for creating new, optically active agrochemicals with potentially improved efficacy and environmental profiles.
• Flavor & Fragrance (F&F) Industry: A potential intermediate for synthesizing high-value, stereochemically defined aroma chemicals and flavorants.
• Academic & Industrial R&D: A valuable tool for chemical research in universities and corporate laboratories focused on stereochemistry and molecular design.

Basic Information

Item	Details
Product Name	(-)-3-Hydroxy-4-(Tetrahydro-2,6,6-Trimethyl-2H-Pyran-2-Yl)Benzoic Acid
CAS No.	55708-43-5
Molecular Formula	C15H20O4
Molecular Weight	264.32 g/mol
Synonyms	(-)-3-Hydroxy-4-(2,6,6-Trimethyltetrahydro-2H-pyran-2-yl)benzoic Acid; 3-Hydroxy-4-(tetrahydro-2,6,6-trimethyl-2H-pyran-2-yl)benzoic Acid, (-)-; 4-(2,6,6-Trimethyltetrahydro-2H-pyran-2-yl)-3-hydroxybenzoic Acid; Benzoic acid, 3-hydroxy-4-(tetrahydro-2,6,6-trimethyl-2H-pyran-2-yl)-, (-)-; (2R)-3-Hydroxy-4-(2,6,6-trimethyloxan-2-yl)benzoic acid (IUPAC); L-Enantiomer of the pyranylbenzoic acid derivative.
EINECS	Contact for details

Quality Control

Our production of (-)-3-Hydroxy-4-(Tetrahydro-2,6,6-Trimethyl-2H-Pyran-2-Yl)Benzoic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (e.e.) and chemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% e.e.
Loss on Drying	≤ 0.5%
Residue on Ignition (Sulfated Ash)	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.